Bextra, Celebrex as Causes for SJS and TEN

SJS is Stevens Johnson Syndrome

TEN is Toxic Epidermal Necrolysis

Bextra, known generically as valdecoxib, and Celebrex, known generically as celecoxib, are drugs reported to cause Stevens Johnson Syndrome and toxic epidermal necrolysis. These drugs are part of a class of prescription pain relievers known as COX-2 inhibitors. Bextra and Celebrex have been prescribed to millions of patients for the treatment of chronic pain and inflammation. Although these drugs provide excellent treatment for the reduction of pain, COX-2 inhibitors are now known to cause many side effects. Vioxx, which is a drug manufactured by Merck and Company, is another COX-2 drug with known, serious adverse side effects. Vioxx, or refocoxib, was recalled in 2004 when researched was released showing the Vioxx lead to a number of heart attack side effects and other cardiovascular problems in patients.

In late 2002, the United States Food and Drug Administration and the manufacturer of Celebrex, Pharmacia, reported that Stevens Johnson Syndrome had been reported in several patients who had taken the drug. As for Bextra, despite early warnings concerning the potential allergic reactions to the drugs, the FDA is still receiving reports of occurrences of SJS and TEN associated with Bextra use. Patients known to have an allergy to sulfa drugs, should not take Bextra.

Doctors and patients should be made aware of the link between sulfa drug allergies and the use of Bextra, Celebrex and other COX-2 inhibitor pain killer drugs. Patients could take these drugs and become susceptible to the serious conditions of Stevens Johnson Syndrome and toxic epidermal necrolysis, without recognizing that they are at risk for these disorders. Stevens Johnson Syndrome causes are not limited to Bextra, Celebrex and other COX-2 inhibitor pain killer drugs. Continue reading to learn about some of the other drugs that have been linked with the incurable skin disorder.

SJS and TEN Legal Remedies

If you or a loved one has been afflicted with Stevens Johnson Syndrome or toxic epidermal necrolysis, then it is possible that the condition was caused by an allergic reaction to a drug. Drug manufacturers have a responsibility to notify physicians and patients of any potential harmful side effects of drugs.

Last Revision: April 25, 2008

MediaFact is a noteworthy Internet resource about drug side effects related to Stevens Johnson Syndromeand Primary Pulmonary Hypertension.