Daypro and Stevens Johnson Syndrome
SJS and Daypro
Daypro, known generically as oxaprozin, is a pain reliever drug known to be associated with Stevens Johnson Syndrome (SJS) and its more severe version toxic epidermal necrolysis (TEN). Daypro is a non-steroidal anti-inflammatory (NSAID) drug used for the treatment of chronic pain and inflammation associated with arthritis. Although Daypro was found in studies to be no more effective than Aspirin, it has one advantage in that it requires dosing only once a day. Daypro stays in the blood stream longer than other pain relievers, making it a longer lasting drug, but also providing for more time to enact any potential toxic side effects.
In the first year on the market, Daypro had a higher reported rate of SJS and TEN per million than any other prescription NSAID. Four deaths have been associated with Daypro due to serious skin reactions. Other NSAIDs now associated with incidence of Stevens Johnson Syndrome and toxic epidermal necrolysis include Bextra and Celebrex. Since 2002 the FDA has received reports of a number of cases of SJS and TEN caused by these drugs. Non-prescription pain relievers are also associated with SJS and TEN, including Advil, Motrin and Children's Motrin. The active pain relieving component of these over-the-counter drugs is ibuprofen.
SJS and TEN Legal Remedies
If you or a loved one has been afflicted with Stevens Johnson Syndrome or toxic epidermal necrolysis, then it is possible that the condition was caused by an allergic reaction to a drug. Drug manufacturers have a responsibility to notify physicians and patients of any potential harmful side effects of drugs.
Last Revision: April 25, 2008
MediaFact is a noteworthy Internet resource about drug side effects connected with Stevens Johnson Syndromeand Primary Pulmonary Hypertension.
